49ers' Christian McCaffrey (Oblique), Deebo Samuel (Shoulder), Trent Williams (Ankle) Injured Against Browns - The Messenger
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49ers’ Christian McCaffrey (Oblique), Deebo Samuel (Shoulder), Trent Williams (Ankle) Injured Against Browns

Both players were involved in a pregame scuffle with the Browns and were taken to the locker room after suffering in-game injuries

San Francisco 49ers wide receiver Deebo Samuel (left) and left tackle Trent Williams (right) are questionable to return against the Cleveland Browns.Michael Zagaris/San Francisco 49ers/Getty Images

San Francisco 49ers running back Christian McCaffrey, wide receiver Deebo Samuel and left tackle Trent Williams all went into the locker room with injuries during Sunday' game against the Cleveland Browns.

McCaffrey injured his oblique, Samuel injured his shoulder and Williams injured his right ankle, which has been sprained a few times before.

All three are questionable to return to the game as the 49ers aimed to stay undefeated against the Cleveland Browns. While Williams returned to the game, Samuel was ruled out for the remainder of the contest.

The Browns and 49ers had a pregame scuffle that included nearly all of both teams' full rosters.

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